PDO threads are suitable for a wide array of people including all skin tones, textures, and age groups. They are most effective on people who have some lax skin they would like to lift and tighten and are especially effective for nasolabial lines, jowls, and jawlines. People with a lot of loose or sagging skin may not notice as dramatic of benefits as someone with mild to moderate laxity since the skin is not being removed, just lifted (It has to go somewhere!)