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Home / Naturopathic Medicine / Hormone Pellet Therapy

Hormone Replacement Therapy

Hormone Pellet Therapy in Gilbert, AZ

Explore personalized hormone pellet therapy in Gilbert, AZ, prescribed and monitored by licensed naturopathic doctors. At Onyx Integrative Medicine, your treatment plan considers your symptoms, health history, hormone levels, and individual goals, with ongoing follow-up to monitor your response.

★★★★★
5.0 · 213 Google reviews

Medically reviewed by
Dr. Stephanie Nichols, NMD

Placed in office
Gilbert, in a short visit

Hormone pellets resting in an open palm, each about the size of a grain of rice
The basics

What are hormone pellets?

A hormone pellet is a small cylinder of hormone, roughly the size of a grain of rice. It is placed just under the skin, usually in the upper hip or buttock, during a short in-office procedure. Over the following months the pellet dissolves completely as the hormone is absorbed, so nothing needs to be taken out later.

Hormone pellets most often deliver testosterone, and for some women estradiol as well. Whether hormone therapy is appropriate for you, and which hormone you need, is determined by your evaluation and lab work with a licensed naturopathic doctor.

How it works

How do hormone pellets work?

Once a pellet is in place, it is absorbed gradually as blood flows past it. Hormone is released continuously rather than in the daily or weekly cycle produced by creams and injections. How much is absorbed, and the hormone levels that result, still vary over time and from patient to patient.

Because absorption depends on your circulation, pellets last different lengths of time in different people. Most patients are seen a few times a year, and your doctor will confirm the schedule that suits you once you have been through a first cycle.

One point to understand before choosing this method: the amount implanted is fixed once the pellet is placed and cannot be adjusted. Absorption and the resulting hormone levels still change over time and differ between patients. That is why your doctor will want an appropriate dose established before recommending pellets.

The naturopathic doctors at Onyx Integrative Medicine in Gilbert, AZ
Candidacy

Who may be a candidate for hormone pellet therapy?

Hormone pellet therapy is considered for patients whose evaluation shows that hormone therapy is appropriate and who prefer a low-maintenance delivery method.
Pellets may be a good fit if
  • Your evaluation and lab work support starting hormone therapy
  • You would rather not manage a daily cream or a regular injection
  • You have used another delivery method and know what dose works well for you
  • You can come to the Gilbert office when each pellet is due
Another method may suit you better if
  • You are starting hormone therapy and your dose is still being established
  • You are pregnant, trying to conceive, or breastfeeding
  • You may need to change or stop treatment quickly
  • You have had a reaction at a previous insertion site

Benefits

Benefits of hormone pellet therapy

Most of the advantages of pellet therapy come from how the hormone is delivered rather than from the hormone itself. Responses vary from person to person.

Fewer daily peaks and dips

Hormone is released continuously rather than in daily or weekly doses, which avoids the peaks and dips of frequent dosing. Individual responses vary.

No daily routine

Nothing to apply each morning and no injections to schedule at home.

A few appointments a year

For most patients, treatment is a small number of short office visits annually.

No transfer to others

Unlike creams and gels, a pellet cannot transfer to a partner or child through skin contact.

Nothing to store or carry

No refrigeration, no supplies and no doses to pack when you travel.

Easier to stay consistent

Staying on schedule does not depend on remembering a daily or weekly step.

Who it is for

Hormone pellets for women and men

Hormone pellets are used for both women and men. Your evaluation determines which hormone is appropriate and whether a pellet is a suitable way to deliver it.

A provider with a patient at Onyx Integrative Medicine in Gilbert, AZ
01For women

Hormone pellets for women

For women, pellets typically deliver testosterone, and in some cases estradiol. Patients often come in during perimenopause or menopause, or because of persistent fatigue, low libido, or changes in mood and sleep.

Your doctor will go through the delivery options available to you, including methods whose dose can be changed more easily, before recommending pellets. Menopause and perimenopause care is where many of these conversations begin.

An Onyx provider in consultation with a male patient in Gilbert, AZ
02For men

Hormone pellets for men

For men, pellets deliver testosterone and are one of several options for testosterone replacement therapy. Treatment begins with lab work and continues with follow-up testing to monitor your response.

Testosterone pellets tend to suit men who have already used another method and know what dose works for them, since the implanted amount cannot be changed once the pellet is placed.

In both cases your doctor confirms the hormone, the dose and the delivery method after reviewing your evaluation.

Delivery methods

Hormone pellets vs. creams, gels, injections and patches

Hormones can be delivered several ways. The practical differences come down to how often you need to think about treatment and how easily the dose can be changed.

Pellets

Placed in office, a few times a year. Continuous release with no daily step to remember. Trade-off: the implanted amount cannot be changed until the next insertion.

Creams

Applied daily at home. The easiest method to adjust, which often suits the period while a dose is being established. Trade-off: easy to miss a day, and care is needed around skin contact.

Gels

Applied daily at home. Grouped with creams clinically; the preparation differs rather than the route. Trade-off: easy to miss a day, and care is needed around skin contact.

Injections

On a set schedule, usually self-administered. Most often used for testosterone, and straightforward to adjust. Trade-off: a routine to keep, and levels move between doses.

Patches

Changed on a set schedule. Worn on the skin, with no daily step to remember. Trade-off: a routine to keep, and levels move between doses.

Oral medication

Taken by mouth, often at night. Most commonly used for progesterone. Trade-off: the route affects how the hormone is processed.

The process

The hormone pellet therapy process

Treatment generally follows these steps.

01

Consultation

A licensed naturopathic doctor reviews your symptoms, health history and goals, and explains which options are available to you.

02

Evaluation and lab work

Hormone testing, along with thyroid, metabolic and nutrient markers where they are relevant. Your doctor interprets the results alongside your history.

03

Pellet insertion

The area is cleaned and numbed with a local anesthetic, a small opening is made, the pellet is placed, and the site is closed with adhesive strips. The procedure takes a few minutes.

04

Follow-up and monitoring

Repeat lab work and a symptom review show how you are responding and help determine when the next pellet is due.

Aftercare

What to expect after pellet insertion

Most patients return to their normal routine the same day. You will be given aftercare instructions at your appointment.
The first few days

Keep the insertion site clean and dry. Some tenderness, bruising or swelling around the site is normal.

Activity

Avoid heavy exercise, swimming, hot tubs and soaking the site for the first few days. Your doctor will confirm when you can return to your usual activity.

Getting back to normal

Most patients drive themselves home after the appointment. Your doctor will tell you what to expect as the site settles.

When to contact the office

Call (480) 531-2557 if the site becomes increasingly painful, red or swollen, if there is drainage or fever, or if you think a pellet has worked its way out.

These are general expectations. Always follow the specific aftercare instructions your doctor gives you.
Safety

Risks and side effects of hormone pellet therapy

Hormone pellet therapy carries two categories of risk: those related to the hormone itself, and those related to the insertion. Your doctor will review the risks that apply to you before treatment begins.
At the insertion site

Tenderness, bruising and minor swelling are common in the first few days. The site can also become irritated or infected, or a pellet can work its way out. Tell your doctor if the site becomes more painful, red or swollen, or if you think a pellet has come out.

Hormone-related effects

As with any hormone therapy, side effects can occur and vary with the hormone and the dose. Follow-up lab work is part of how these are identified and managed.

Your health history matters

Some conditions and medications affect whether hormone therapy is appropriate. Your full history is reviewed before treatment begins, so bring your current medication list to your consultation.

Monitoring is part of treatment

Hormone therapy is followed with repeat testing and symptom review rather than left unchanged, and your doctor uses those results to decide what happens at the next visit.

Pregnancy, conception and breastfeeding

Tell your doctor before treatment if you are pregnant, trying to conceive, planning a pregnancy, or breastfeeding, since this affects whether hormone therapy is appropriate for you. A pellet is not designed to be taken out, and removing one requires a minor procedure, so contact the office right away if you become pregnant or think you might be while a pellet is in place.

Treatment Timeline

How long do hormone pellets last?

Hormone pellets are designed to release hormone gradually as the pellet dissolves, so you do not need to apply or inject medication every day or week. How long a pellet lasts varies from person to person and depends on the hormone, dose, metabolism, symptoms, and individual response.
Many patients receive another pellet periodically as the previous one is absorbed, but there is no single schedule that works for everyone. Your provider determines when another insertion may be appropriate based on your symptoms, hormone levels when clinically appropriate, and how you are responding to treatment.
Because a pellet cannot be easily adjusted once it has been inserted, your doctor establishes the dose carefully before placement. If your needs change, your provider can discuss whether a different delivery method may offer more flexibility.

Not sure which hormone delivery method is right for you? Start with an evaluation.

Why Onyx

Why choose Onyx for hormone pellet therapy in Gilbert, AZ?

Onyx Integrative Medicine is an integrative clinic in Gilbert with three licensed naturopathic doctors on staff. Hormone care here starts with an individualized evaluation rather than a standard protocol, and we work with every common delivery method, so your doctor can weigh your results, your symptoms and your preferences before recommending one. Your care is supervised by an NMD from the first consultation through follow-up testing.

  • Individualized hormone evaluationYour symptoms, history and lab results are reviewed together before any treatment is recommended.
  • Care supervised by licensed NMDsThree naturopathic doctors on staff at one Gilbert clinic.
  • Multiple delivery optionsPellets, creams, gels, injections, patches and oral preparations.
  • Appropriate lab testingHormone, thyroid, metabolic and nutrient markers, ordered when they are relevant to your case.
  • Ongoing monitoringFollow-up lab work and symptom review guide adjustments over time.

Meet your doctors

Dr. Stephanie Nichols, NMD

Onyx's founder, working mainly in women's hormones, thyroid health and the conditions that overlap with both.

Founder · Naturopathic Physician

Dr. Kasey Nichols, NMD

Connects hormones, digestion, metabolism and mindset, and treats thyroid and gut concerns at the root.

Co-Founder · Naturopathic Physician

Dr. Chelsea Deveson, NMD

Focused on the root causes of chronic disease. Dr. Chelsea treats thyroid conditions, adrenal fatigue, PCOS (now officially PMOS), perimenopause and digestive issues with individualized, lab-guided care.

Naturopathic Physician · Root-Cause Care

In their own words

What our patients say

Real Onyx patients, talking about their own care. Individual experiences vary.
Read all reviews

Locations

Hormone pellet therapy near you in Gilbert and the East Valley

Onyx Integrative Medicine & Aesthetics is on W Elliot Rd in Gilbert and treats hormone patients from across the East Valley. Pellet insertion is performed in the office. Consultations and results reviews can often be done by telemedicine, and lab work is drawn at LabCorp, Sonora Quest or Patient's Choice, whichever is most convenient for you.

GilbertChandlerMesaQueen CreekTempeSan Tan ValleyApache Junction

Onyx Integrative Medicine & Aesthetics1425 W Elliot Rd Ste. 104, Gilbert, AZ 85233(480) 531-2557

FAQ

Questions About Hormone Pellet Therapy

It varies from person to person. A pellet dissolves as your blood supply absorbs it, so circulation, activity level and body composition all affect the pace. Most patients need a small number of insertions each year. Your doctor will give you a clearer picture of your own schedule after your first cycle and your follow-up lab work.

The area is numbed with a local anesthetic first, so most patients describe pressure rather than pain during the procedure itself. The site can feel tender or bruised for a few days afterwards. The appointment takes only a few minutes and most people drive themselves home.

A pellet is designed to dissolve completely, so it is not intended to be taken out once it is placed, and it continues releasing hormone until it is absorbed. If removal becomes medically necessary, a pellet can be taken out, but that requires a minor procedure rather than a routine visit. This is the main reason your doctor will want an appropriate dose established first. If you think you may need to change or stop treatment quickly, tell your doctor before anything is placed so another delivery method can be considered.

Partly, and the distinction matters. TESTOPEL is an FDA-approved testosterone pellet, approved for testosterone replacement in certain males. Compounded hormone pellets, which are prepared by a compounding pharmacy, are not FDA-approved finished products. Using testosterone pellets in women is off-label, which means it is not an FDA-approved use. Your doctor can tell you which preparation is being recommended for you and why.

Not better, but differently. The hormone is the same. What a pellet changes is the delivery: continuous release with nothing to remember day to day, in exchange for an implanted amount that cannot be adjusted until the next insertion. Absorption and the levels that result still vary over time and between patients. Which method suits you depends on your lab results, your symptoms and how much flexibility your plan needs, which is why the choice is made after your evaluation.

There are two categories. The first relates to the hormone itself and applies to any delivery method, which is why hormone therapy is monitored with follow-up testing. The second relates to the procedure: the site can be tender or bruised, and it can become irritated or infected, or a pellet can work its way out. Tell your doctor if you are pregnant, trying to conceive or breastfeeding, since that affects whether hormone therapy is appropriate. Your doctor will go through the risks that apply to your history before treatment begins.

Onyx is primarily cash-pay, and HSA and FSA funds are accepted. Some naturopathic visits may be eligible for out-of-network reimbursement. Your cost has separate parts: the consultation, any lab work, which is billed by the laboratory, and the treatment itself if it is prescribed. Nothing is ordered before it has been explained to you. Call (480) 531-2557 to go through your situation. A deposit secures your first appointment.

No. Pellets suit patients who would rather not manage a daily step, but they are one option among several. Creams, gels, injections, patches and oral medication are all available, and your doctor will recommend the method that best suits you, taking your results and your preferences into account.

Next step

Is hormone pellet therapy right for you?

That depends on your hormone levels, your symptoms and your health history. Book a consultation with a licensed naturopathic doctor at Onyx in Gilbert and you will get a clear recommendation on whether hormone therapy is appropriate and which delivery method fits you.

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